1st European Ovary Workshop
EMBO Workshop on Ovarian Biology
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1st European Ovary Workshop
All About Ovaries
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Sunday
, February 16
TBA
15:00 •
Registration
17:00 •
Welcome reception
20:00 •
Dinner
Monday
, February 17
TBA
07:00 •
Registration
08:30 •
Opening ceremony
09:00 •
Keynote 1: Gonadal sex determination
09:30 •
Keynote 2: Meiosis and oogenesis
10:00 •
Cohesin dynamics determine oocyte quality throughout the mammalian reproductive lifespan
10:15 •
SMYD3 as a key epigenetic regulator of meiotic maturation and developmental competence in ovine oocytes
10:15 •
Epigenetic regulation of female reproductive aging
10:15 •
Preventing Supernumerary Oocyte Formation by Restricting Synaptonemal Complex Maintenance
10:15 •
Investigating the impact of pubertal onset on cohesion weakening in mouse oocytes
10:15 •
Reconstructing the ultrastructure of conserved ovarian intercellular bridges (ICBs)
10:15 •
Morphological assessment of competence: creating a model for predicting blastocyst formation and euploidy status from oocyte characteristics
10:45 •
Break
11:15 •
Keynote: Theca cells – the forgotten cells of the ovary
11:45 •
Mechanical control of mammalian folliculogenesis by theca cells and its implications in ageing
12:00 •
Luteinizing hormone (LH)- and choriogonadotropin (hCG)-dependent receptor trafficking is required to maintain ligand-specific signalling
12:00 •
Molecular landscape of folliculogenesis and oogenesis across ovarian lifecycle stages
12:00 •
Revealing ovarian homeostasis in Drosophila: A new model for ovarian physiology
12:00 •
Isolation and propagation of human ovarian theca cells
12:00 •
Isolation and characterization of extracellular vesicles from maturation media conditioned by bovine oocytes
12:00 •
SLIT1 and SLIT2 act redundantly through AKT pathway in response to gonadotropins without exclusively signaling via ROBO1 in mouse follicular granulosa cells
12:00 •
Single-cell transcriptomics show a cell cycle response in ovarian mural granulosa cells of sows following a negative energy balance during lactation
12:00 •
The effect of luteinizing hormone (LH) in modulating Anti-Müllerian hormone (AMH) pathway in human granulosa cells
12:00 •
Distinct differences in luteinization dynamics of cultured human granulosa cells from small antral follicles and preovulatory follicles
12:30 •
Lunch + Networking event
14:30 •
Translational strategies targeting the ovarian microenvironment to improve reproductive longevity
15:00 •
Single cell and spatial multiomics analysis of the ovary across the lifespan
15:15 •
Preliminary results on the comparison of different techniques for isolation of extracellular vesicles from equine follicular fluid
15:15 •
Development of a decellularized bovine ovarian tissue scaffold and its application in 3D culture of secondary follicles in a medium enriched with resveratrol-loaded nanoparticles
15:15 •
IGF-1, EGF and dbcAMP orchestration for gap-junction restoration between oocytes and cumulus cells
15:15 •
Mapping the human ovarian cortex: unravelling the proteomics landscape across life stages and chemotherapy exposures
15:15 •
A novel cellular player in ovarian biology: telocytes in the intraovarian stroma
15:15 •
Assessing the ovarian microbiome: lack of a distinguishable microbial signature beyond contamination
15:15 •
AMH signaling in the ovary is mediated by stromal fibroblasts. Stroma-follicle interactions as a key to understanding follicle activation regulation
15:15 •
Proteomic profiling reveals the molecular signature of chemotherapy-induced microenvironmental alterations in the human ovary
15:15 •
Extracellular vesicles in the ovarian follicle in health and disease: do they play only trivial roles in molecular cellular communication?
15:45 •
Break
16:15 •
Keynote 1: Contribution of mechanical force to microenvironment for oocyte dormancy
16:45 •
Keynote 2: New methods for induced ovulation and gamete derivation in an endangered marsupial mammal
17:15 •
Innovative Poly(epsilon-caprolactone)(PCL) electrospun patterned scaffolds: shaping the future of ovarian tissue engineering
17:30 •
Silk-Ovarioids: Establishment and characterization of human ovarian primary cells 3D-model system
17:30 •
Generation of novel human ovarian cell models in vitro
17:30 •
The effect of the mitochondrial-targeted antioxidant Mitoquinol in human follicles and ovarian tissue in vitro
17:30 •
Molecular and ultrastructural effects of in vitro culture on human ovarian cortical samples
17:30 •
Evaluation of adeno-associated virus (AAV)-mediated transduction of dissociated mouse ovarian cells
17:30 •
Ovarian rejuvenation: neonatal cell replacement revives age-related loss in ovarian self-organisation
17:30 •
The role of in vitro culture medium in shaping human ovarian preantral follicle development and ECM secretion
17:30 •
Developing an in vitro ovary model for the prolonged culture of mouse follicles
17:30 •
Development of the in vitro culture of human preantral follicles for restoration of fertility in cancer patients
17:30 •
Developing mouse ovarian organoids to explore reproductive health and disease
18:00 •
Poster Session 1 + Drinks
20:00 •
Welcome Dinner Party – Quiz Night
Tuesday
, February 18
TBA
09:00 •
Keynote 1: Age-related loss of heterochromatin in oocytes leads to meiotic molecular defects and maturation deficiency
09:30 •
Keynote 2: Forever young: lessons from the naked mole-rat ovary
10:00 •
SkQ1 treatment prevents ovarian aging in mice
10:00 •
Genetic and anthropometric determinants of age-related ovarian follicular reserve
10:30 •
Impact of minipubertal gonadotropin and estradiol surges on ovaries before puberty, during reproductive life and aging in mice
10:30 •
Epigenetic aging in oocytes
10:30 •
Effects of estradiol treatment on body composition in a mouse model of menopause: impacts on fat distribution, lean mass, and bone volume
10:30 •
Age and Physical Activity Modulate the miRNA Cargo contained in Extracellular Vesicles derived from Follicular Fluid
10:30 •
Metabolic pathways to reproductive longevity: BCAA and DR insights from C. elegans
10:30 •
Genetic links between ovarian ageing, cancer risk and de novo mutation rates
10:30 •
Exploring the role of interferon signaling as a modifier of DNA-damage syndrome and gonadal ageing
10:30 •
Large ovarian reserve and lack of aging-associated oocyte quality decline in non-mouse rodents
10:30 •
Investigating the effects of reduced SECISBP2 expression on ovarian function and aging in mice
11:00 •
Break
11:30 •
Keynote: New neuroendocrine pathways in the regulation of ovarian function
12:00 •
Revealing the secrets of ovulation
12:15 •
Vasorin Involvement in the Maintenance of the Ovarian Follicular Reserve
12:15 •
HIPK2 and IKK𝛃 dependent guardian of germ cells TAp63𝛂 phosphorylation is crucial for its stability and ovarian reserve maintenance
12:15 •
The Dummerstorf high-fertility mouse line 1 – a worldwide unique model for increased female reproductive performance
12:15 •
Impact of the P4 antagonist RU486 on VEGF and its receptor signaling during the in vivo shift from the preovulatory to the periovulatory phase of ovarian follicles
12:15 •
Nucleoporin107 regulates EGFR signaling in the ovarian soma, necessary for proper oocyte differentiation
12:15 •
Characterization of cellular populations in the fetal ovary of the rabbit Oryctolagus cuniculus
12:15 •
Development of human ovarian spheroids as an innovating 3D model to study female hormone-related disorders
12:15 •
New potential role of Luteinizing Hormone in the maintenance and survival of ovarian reserve
12:15 •
Nucleoporin107 is a critical determinant of soma-germline communication, essential for ovarian development and function
12:50 •
Sponsor Talk: Cryo Bio System
13:00 •
Sightseeing: Boat trip + lunch
20:00 •
Dinner
Wednesday
, February 19
TBA
09:00 •
Keynote: In vitro maturation of immature oocytes in women with PCOS
09:30 •
The effect of chronic inflammation on female fertility, oocyte epigenetics, and oocyte quality
09:45 •
TUBB8 mutations and oocyte immaturity: screening, IVF outcomes and therapeutical perspectives : a systematic review
09:45 •
Mesenchymal stromal cell secretome and its evaluation in the treatment of Polycystic Ovary Syndrome
09:45 •
Mild chronic variable stress promotes female fertility via the ovarian CRF receptor
09:45 •
The power of near-infrared photobiomodulation therapy on rescue in vitro maturation of human oocytes
09:45 •
An investigation of the genetic association between low ovarian reserve and female malignancy
09:45 •
Challenges in managing FOXL2-related follicular arrest: when modern IVF and tissue preservation fall short
09:45 •
Follicular fluid concentrations of the vitamin D metabolite 24,25(OH)2D3 are positively associated with live birth rate after ART
10:15 •
Break
10:45 •
Keynote: Assessing toxicity in human ovaries - from exposures and epidemiology to in vitro models
11:15 •
Impact of cannabis on human oocytes and IVF outcomes: an extensive in vitro and clinical investigation
11:30 •
Scoping review of the association between ultra-processed food and female fertility: current evidence and research gaps
11:30 •
Perinatal exposure to Bisphenol A impairs the ovarian follicle dynamics and its extracellular milieu
11:30 •
Repercussions of estrogen replacement therapy against BPA-induced ovarian disruption in a rodent model
11:30 •
Effects of phthalates on the 3D spheroid cell culture as a model for the human ovarian extracellular matrix
11:30 •
Single-cell insights on the effects of the phthalate metabolite MEHP on the human ovary in vitro
11:30 •
Cannabis alters human granulosa cell steroidogenesis and luteinization
11:30 •
Secondary effects of thyroid hormone disrupting chemicals on the ovary transcriptome – identification of effect biomarkers
11:30 •
Hypo- and Hyper-methylation in oocytes correlates with altered folliculogenesis following exposure to an estrogenic endocrine disruptor
12:00 •
Impact of maternal aging on oocyte DNA repair and female fertility
12:00 •
Generation of functional oocytes by sex chromosome correction in vitro
12:00 •
Investigating ribosome dynamics in the aging mammalian oocyte
12:00 •
The Multispecies Ovary Tissue Histology Electronic Repository (MOTHER): A resource for science, education and data sharing
13:00 •
Lunch
14:30 •
Keynote: New insights to ovarian tissue cryopreservation and transplantation
15:00 •
Ovarian tissue after thawing: metabolic recovery and hormonal effects in follicle preservation, apoptosis and angiogenesis
15:30 •
Optimization of freezing and thawing protocols for human ovarian tissue cryopreservation through thermophysical characterisation of freezing medium by Differential Scanning Calorimetry
15:30 •
Can UCMSCs improve the integrity and mitochondrial function of cryopreserved ovarian grafts?
15:30 •
Antioxidant potential of eugenol derivatives: a preliminary study for ovarian tissue cryopreservation
15:30 •
Effect of prolonged cooling on metabolism of ovarian tissues in transport: TOM20 as a biomarker of mitochondrial function
15:30 •
Biomechanical assessment of human ovarian cortex after vitrification and slow freezing procedures
15:30 •
Molecular regulation of in vitro matured human oocytes in connection with ovarian tissue cryopreservation
15:30 •
Evaluating follicular outcomes during ex vivo photodynamic therapy in ovarian tissue
15:30 •
Effect of freezing and culturing ovarian tissue on follicle development in prepubertal girls
15:30 •
A novel platform for cutting-edge cancer research is a tumor-infiltration mimicking model of contaminated ovarian tissue
15:30 •
Optimization of ovarian tissue transplantation through biomaterials: a scoping review
15:30 •
What is the impact of transport time on the quality of ovarian tissue prior to cryopreservation? A comparison of post-transplantation success rates with findings at the proteomic, gene expression and histological levels
15:30 •
Circulating cell-free DNA and miR 502-3p are new predictive biomarkers of fertility preservation outcome in patients with breast cancer
16:15 •
Break
16:45 •
Activation or Apoptosis: Combined suppression of intrinsic and extrinsic follicle activation pathways completely prevents cyclophosphamide-induced follicle loss, while DNA damage doesn't end in oocyte apoptosis
17:00 •
Clinical and ethical perspectives of performing ovarian stimulation and oocyte cryopreservation in adolescents: 6 years experience from a tertiary centre
17:00 •
Evaluating the gonadotoxicity of carboplatin and paclitaxel exposure on the ovary from young breast cancer patients carrying a BRCA mutation
17:00 •
Fertility preservation for girls undergoing cancer treatments or other gonadal toxic therapies
17:00 •
Use of long-acting GnRH trigger for fertility preservation patients
17:00 •
Molecular and functional impact of X-ray on primary ovarian cells
17:00 •
The protective effects of Aloe vera extract against doxorubicin-induced degeneration in mice ovarian follicles and stromal cells
17:00 •
Use of factors released from human adipose stem cells for ovarian tissue regeneration
17:00 •
Anti-Mullerian hormone protects human ovarian follicles and stromal cells from immediate and sustained cyclophosphamide-induced damage in vitro
17:00 •
From Storage to Survivorship: Exploring the Experiences and Needs of Childhood Cancer Survivors with Stored Ovarian Tissue
17:30 •
Keynote: Harmony in diversity – ovarian biology in wild animal species
18:00 •
Poster Session 2 + Drinks
20:00 •
Gala Dinner
Thursday
, February 20
TBA
09:00 •
Keynote: Importance of patient and public involvement
09:30 •
Panel discussion
10:00 •
Break
10:30 •
Keynote: Coordinating ovarian research
10:50 •
Keynote: Ethics in ovarian research
11:20 •
Keynote: Nature’s SAFE & The Rhino Fertility Project
11:40 •
Closing ceremony
12:00 •
Lunch and Goodbye
Filter By Date
Feb 16
-
20, 2025
Sunday
, February 16
Monday
, February 17
Tuesday
, February 18
Wednesday
, February 19
Thursday
, February 20
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Lagos, Portugal
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Break
Ceremony
All
Closing Ceremony
Opening ceremony
Event
All
Dinner
Networking
Flash talk
All
Female Fertility Preservation
Female Fertility Preservation (Cont)
Follicular Cells & Signaling
Generating Oocytes in vitro & Bioengineering
Meiosis & Ploidy
Ovarian Aging
Ovarian Dysfunction & ART
Ovarian Microenvironment
Ovarian Reserve & Endocrinology
Ovarian Toxicology & Environmental Impacts
Keynote
All
Female Fertility Preservation
Follicular Cells & Signaling
Generating Oocytes in vitro & Bioengineering
Meiosis & Ploidy
Organization & Ethics
Ovarian Aging
Ovarian Dysfunction & ART
Ovarian Microenvironment
Ovarian Reserve & Endocrinology
Ovarian Toxicology & Environmental Impacts
Patient and public involvement in science
Wildlife Conservation
Meal
All
Dinner
Lunch
Panel
All
Patient and public involvement in science
Poster
All
Drinks
Registration
All
-
Registration
Short talk
All
Award Session: Best Scoring Abstracts
Female Fertility Preservation
Follicular Cells & Signaling
Generating Oocytes in vitro & Bioengineering
Meiosis & Ploidy
Ovarian Aging
Ovarian Dysfunction & ART
Ovarian Microenvironment
Ovarian Reserve & Endocrinology
Ovarian Toxicology & Environmental Impacts
Sponsor Talk
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Dates
Sunday
, February 16
Monday
, February 17
Tuesday
, February 18
Wednesday
, February 19
Thursday
, February 20
Session Type
Break
Ceremony
All
Closing Ceremony
Opening ceremony
Event
All
Dinner
Networking
Flash talk
All
Female Fertility Preservation
Female Fertility Preservation (Cont)
Follicular Cells & Signaling
Generating Oocytes in vitro & Bioengineering
Meiosis & Ploidy
Ovarian Aging
Ovarian Dysfunction & ART
Ovarian Microenvironment
Ovarian Reserve & Endocrinology
Ovarian Toxicology & Environmental Impacts
Keynote
All
Female Fertility Preservation
Follicular Cells & Signaling
Generating Oocytes in vitro & Bioengineering
Meiosis & Ploidy
Organization & Ethics
Ovarian Aging
Ovarian Dysfunction & ART
Ovarian Microenvironment
Ovarian Reserve & Endocrinology
Ovarian Toxicology & Environmental Impacts
Patient and public involvement in science
Wildlife Conservation
Meal
All
Dinner
Lunch
Panel
All
Patient and public involvement in science
Poster
All
Drinks
Registration
All
-
Registration
Short talk
All
Award Session: Best Scoring Abstracts
Female Fertility Preservation
Follicular Cells & Signaling
Generating Oocytes in vitro & Bioengineering
Meiosis & Ploidy
Ovarian Aging
Ovarian Dysfunction & ART
Ovarian Microenvironment
Ovarian Reserve & Endocrinology
Ovarian Toxicology & Environmental Impacts
Sponsor Talk
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